Location: 1187 Postle Hall
Soft Materials to Build Hard Tissues
David J. Mooney, PhD
While bone is a hard tissue, hydrogels (soft materials) are often utilized to engineer or regenerate bone. Current mechanotransduction studies focus on the role of gel stiffness on stem cell differentiation, but we find that both hydrogel stiffness and viscoelasticity dramatically impact stem cell fate. To address the impact of these properties at the single cell level, a microfluidic-based method for encapsulating single cells in a thin layer of hydrogel has been developed.
David Mooney is the Pinkas Family Professor of Bioengineering in the Harvard School of Engineering and Applied Sciences, and a Core Faculty Member of the Wyss Institute. His laboratory designs biomaterials to make cell and protein therapies effective and practical approaches to treat disease. He is a member of the National Academy of Engineering, the National Academy of Medicine, and the National Academy of Inventors. He has won numerous awards, including the Clemson Award from the SFB, MERIT award from the NIH, Distinguished Scientist Award from the IADR, Phi Beta Kappa Prize for Excellence in Undergraduate Teaching, and the Everett Mendelsohn Excellence in Mentoring Award from Harvard College. His inventions have been licensed by numerous companies, leading to commercialized products, and he is active on industrial scientific advisory boards.
Lunch will be provided. For more information: 614-688-3435 or firstname.lastname@example.org.
One CE credit available.