Dimitris N. Tatakis, DDS, PhD

Dimitris Tatakis, DDS, PhD
Academic Title
Director for Global Initiatives
Graduate Periodontics Program Director

Dental Degree
National and Kapodistrian University School of Dentistry, Greece, 1982

State University of New York at Buffalo School of Dental Medicine, 1990, Oral Biology (Cell Biology)

State University of New York at Buffalo School of Dental Medicine, 1990, Periodontics 

American Board of Periodontology 

Academic Division
Office Address

4121 Postle Hall
305 W. 12th Ave.
43210 OH
United States

Research Interests

Clinical and translational research with an emphasis on periodontal regenerative surgical outcomes and periodontal wound healing, and focus on host factors that determine regenerative and healing outcomes.


The list below includes select publications. For a full list of PubMed articles, follow this link.

Kandaswamy E, Sakulpaptong W, Guo X, Ni A, Powell HM, Tatakis DN, Leblebicioglu B. Titanium as a possible modifier of inflammation around dental implants. Int J Oral Maxillofac Implants 2022 37:381-390. doi: 10.11607/jomi.9271. PMID: 35476868

Kofina V, Lindholm D, Harunani A, Dentino AR, Singh M, Tatakis DN. Post-surgical emergency after-hours calls: prevalence, concerns, and management. J Dent Educ 2022: 86:814-822. doi: 10.1002/jdd.12888. PMID: 35118665

Miguel MMV, Mathias-Santamaria IF, Rossato A, Ferraz LFF, Rangel TP, Casarin RCV, Tatakis DN, Santamaria MP. Enamel matrix derivative effects on palatal mucosa wound healing: randomized clinical trial. J Periodontal Res 2021; 56:1213–1222.  doi:10.1111/jre.12934. PMID: 34541683

Sendyk DI, Souza NV, César Neto JB, Tatakis DN, Pannuti CM. Selective outcome reporting in root coverage randomized clinical trials. J Clin Periodontol 2021; 48: 867-877. doi: 10.1111/jcpe.13451. PMID: 33745136

Silva CO, Rezende RI, Mazuquini AC, Leal VC, Amaral GSA, Guo X, Tatakis DN. Aesthetic crown lengthening and lip repositioning surgery: Pre- and post-operative assessment of smile attractiveness. J Clin Periodontol 2021; 48: 826-833. doi: 10.1111/jcpe.13461. PMID: 33745186

Andijani RI, Paramitha V, Guo X, Deguchi T, Tatakis DN. Lip repositioning surgery for gummy smile: 6-month clinical and radiographic lip dimensional changes. Clin Oral Investig 2021; 25:5907-5915. doi:10.1007/s00784-021-03896-7. PMID: 33745100

Altingöz SM, Kurgan Ş, Önder C, Serdar MA, Ünlütürk U, Uyanik M, Başkal N, Tatakis DN, Günhan M. Salivary and serum oxidative stress biomarkers and advanced glycation end products in periodontitis patients with or without diabetes: a cross-sectional study. J Periodontol 2021; 92:1274–1285. doi: 10.1002/JPER.20-0406.  PMID: 33277933

Wang Y, Tatakis DN. Integrative mRNA/miRNA expression analysis in healing human gingiva. J Periodontol 2021; 92:863-874. doi: 10.1002/JPER.20-0397. PMID: 32857863

Doshi A, McAuley JW, Tatakis DN. Topical phenytoin effects on palatal wound healingJ Periodontol 2021; 92:409–418. doi: 10.1002/JPER.20-0340. PMID: 32761909

Kofina V, Demirer M, Erdal BS, Eubank TD, Yildiz VO, Tatakis DN, Leblebicioglu B. Bone grafting history affects soft tissue healing following implant placement. J Periodontol 2021; 92:234–243. doi:  10.1002/JPER.19-0709. PMID: 32779206

Neves FLDS, Augusto Silveira C, Mathias-Santamaria IF, Miguel MMV, Ferraz LFF, Casarin RCV, Sallum EA, Tatakis DN, Santamaria MP. Randomized clinical trial evaluating single maxillary gingival recession treatment with connective tissue graft and tunnel or trapezoidal flap: 2-year follow-up. J Periodontol 2020; 91:1018–1026. doi: 10.1002/JPER.19-0436. PMID: 31867724

Wang Y, Anderson EP, Tatakis DN. Whole transcriptome analysis of smoker palatal mucosa identifies multiple downregulated innate immunity genes. J Periodontol 2020; 91:756-766. doi: 10.1002/JPER.19-0467.  PMID: 31682009

Leblebicioglu B, Alssum L, Eubank TD, Yildiz VO, Tatakis DN. Wound fluid cytokine profile following bone regeneration procedures. J Oral Implantol 2020; 46:107–113. doi: 10.1563/aaid-joi-D-19-00061. PMID: 31909694

Chavez MB, Kolli TN, Tan MH, Zachariadou C, Wang C, Embree M, Dos Santos EJL, Nociti FH Jr, Wang Y, Tatakis DN, Agarwal G, Foster BL. Loss of discoidin domain receptor 1 predisposes mice to periodontal breakdown. J Dent Res 2019; 98:1521-1531. doi: 10.1177/0022034519881136. PMID: 31610730

César Neto JB, Cavalcanti MC, Sekiguchi RT, Pannuti CM, Romito GA, Tatakis DN. Root coverage for single deep gingival recessions: outcomes based on a decision-making algorithm. Int J Dent 2019; 2019: 1830765. doi:10.1155/2019/1830765. PMID: 30805000

Andijani RI, Tatakis DN. Hypermobile upper lip is highly prevalent among patients seeking treatment for gummy smile. J Periodontol 2019; 90:256–262. doi: 10.1002/JPER.18-0468. PMID: 30367736

Chapple ILC, Mealey BL, Van Dyke TE,  Bartold PM, Dommisch H, Eickholz P, Geisinger ML, Genco RJ, Glogauer M, Goldstein M, Griffin TJ, Holmstrup P, Johnson GK, Kapila Y, Lang NP, Meyle J, Murakami S, Plemons J, Romito GA, Shapira L, Tatakis DN, Teughels W, Trombelli L, Walter C, Wimmer G, Xenoudi P, Yoshie H. Periodontal health and gingival diseases and conditions on an intact and a reduced periodontium: Consensus report of workgroup 1 of the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions. J Clin Periodontol 2018; 45 (Suppl. 20):S68-S77. PMID: 29926499

Trombelli L, Farina R, Silva CO, Tatakis DN. Plaque-induced gingivitis: Case definition and diagnostic considerations. J Clin Periodontol 2018; 45 (Suppl. 20):S44-S67. PMID: 29926492

Alssum L, Eubank TD, Roy S, Erdal BS, Yildiz VO, Tatakis DN, Leblebicioglu B. Gingival perfusion and tissue biomarkers during early healing of post-extraction regenerative procedures: a prospective case series. J Periodontol 2017; 88:1163-1172. PMID: 28644107

Santamaria MP, Neves FLDS, Silveira CA, Mathias IF, Fernandes-Dias SB, Jardini MAN, Tatakis DN. Connective tissue graft and tunnel or trapezoidal flap for the treatment of single maxillary recessions: a randomized clinical trial. J Clin Periodontol 2017; 44:540-547. PMID: 28231619

Wang Y, Tatakis DN. Human gingiva transcriptome during wound healing. J Clin Periodontol 2017; 44:394-402. PMID: 28005267

Pilalas I, Tsalikis L, Tatakis DN. Prerestorative crown lengthening surgery outcomes: A systematic review. J Clin Periodontol 2016; 43:1094-1108PMID: 27535216

Chambrone L, Tatakis DN. Long-term outcomes of untreated buccal gingival recessions. A systematic review and meta-analysis. J Periodontol 2016; 87:796-808. PMID: 26878749

Delima SL, Kumar PS, Tatakis DN. Bacterial community shifts during healing of palatal wounds: comparison of two graft harvesting approaches. J Clin Periodontol 2016; 43:271-278. PMID: 12226661520

Tatakis DN, Chambrone L. The effect of suturing protocols on coronally advanced flap root-coverage outcomes: A meta-analysis. J Periodontol 2016; 87:148-155. PMID: 26447751

Silva CO, Soumaille JM, Marson FC, Progiante PS, Tatakis DN. Aesthetic crown lengthening: periodontal and patient-centred outcomes. J Clin Periodontol 2015; 42:1126-1134. PMID: 26613260

Leblebicioglu B, Hegde R, Yildiz V, Tatakis DN. Immediate effects of tooth extraction on ridge integrity and dimensions. Clin Oral Investig 2015; 19:1777-1784. PMID: 25567485

Tatakis DN, Chambrone L, Allen EP, Langer B, McGuire MK, Richardson CR, Zabalegui I, Zadeh HH. Periodontal soft tissue root coverage procedures: a consensus report from the AAP Regeneration Workshop. J Periodontol 2015; 86(Suppl.):S52-S55. PMID: 25315018

Chambrone L, Tatakis DN. Periodontal soft tissue root coverage procedures: a systematic review from the AAP Regeneration Workshop. J Periodontol 2015; 86(Suppl.):S8-S51. PMID: 25644302

Dental Emergency Care Clinic

7:30 a.m.-12 p.m.

7:30 a.m.-10:30 a.m.

Student Dental Clinics

8:00 a.m.-4:00 p.m.

Ohio State Dental Faculty Practice

7:30 a.m.-4:30 p.m.

Upper Arlington Dental Clinic

7:30 a.m.-5:30 p.m.

7:30 a.m.-4:30 p.m.

7:30 a.m.-12:30 p.m.