Faculty Biographies

Academic Title

Chair, Division of Oral and Maxillofacial Surgery and Anesthesiology

The Larry J. Peterson Endowed Professor

Academic Division

Oral and Maxillofacial Surgery and Dental Anesthesiology

Education

Dental Degree
Creighton University, 1983

Certificate
University of Oklahoma, 1987, Oral and Maxillofacial Surgery

Contact

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Email:

larsen.5@osu.edu

Phone:

Academic office: 614-292-9731; Patient appointments and referrals: 614-292-5144

Office Address:

2170 Postle Hall

305 W. 12th Ave.

Columbus, OH 43210

Research Interests

Translational studies and clinical applications relevant to oral cancer chemoprevention. Studies entail determination of pharmacokinetic properties of chemopreventive formulations prior to clinical use and human clinical trials to determine efficacy of local delivery chemopreventive formulations on premalignant oral lesions.

Clinical Interests

Reconstruction of patients with complex restorative needs utilizing dental implants / this includes surgical preparation of sites requiring grafts to restore jaw continuity and bone volume, as well as implant treatment in children and adolescents, particularly those with multiple missing teeth; Orthognathic surgery; Management of patients with cleft lip and palate, focusing on participation in a cleft team emphasizing grafting of alveolar cleft patients and orthognathic surgery in cleft patients; Routine dentoalveolar surgery, including extraction of third molars (wisdom teeth).

Publications

Susan R. Mallery; Meng Tong; Brian S. Shumway; Alice E. Curran; Peter E. Larsen; Gregory M. Ness; Kelly S. Kennedy; George H. Blakey; George M. Kushner; Aaron M. Vickers; et al. - Topical application of a mucoadhesive freeze-dried black raspberry gel induces clinical and histologic regression and reduces loss of heterozygosity events in premalignant oral intraepithelial lesions: Results from a multicentered, placebo-controlled clinical trial Clinical Cancer Research. 2014;20(7):1910-1924.

Do-Gyoon Kim; Sarandeep S. Huja; Boon Ching Tee; Peter E. Larsen; Kelly S. Kennedy; Hua-Hong Chien; Jin Whan Lee; Hai Bo Wen - Bone ingrowth and initial stability of titanium and porous tantalum dental implants: A pilot canine study Implant Dentistry. 2013;22(4):399-405.

Henning Schliephake; Matthias Rödiger; Keith Phillips; Edwin A. McGlumphy; Guillermo E. Chacon; Peter Larsen - Early loading of surface modified implants in the posterior mandible - 5‑year results of an open prospective non-controlled study Journal of Clinical Periodontology. 2012;39(2):188-195.

Andrew S. Holpuch; Maynard P. Phelps; Kashappa-Goud H. Desai; Wei Chen; George M. Koutras; Byungdo B. Han; Blake M. Warner; Ping Pei; Garrett A. Seghi; Meng Tong; et al. - Evaluation of a mucoadhesive fenretinide patch for local intraoral delivery: A strategy to reintroduce fenretinide for oral cancer chemoprevention Carcinogenesis. 2012;33(5):1098-1105.

Susan R. Mallery; Deric E. Budendorf; Matthew P. Larsen; Ping Pei; Meng Tong; Andrew S. Holpuch; Peter E. Larsen; Gary D. Stoner; Henry W. Fields; Kenneth K. Chan; et al. - Effects of human oral mucosal tissue, saliva, and oral microflora on intraoral metabolism and bioactivation of black raspberry anthocyanins Cancer Prevention Research. 2011;4(8):1209-1221.

Avi E. Stein; Edwin A. McGlumphy; William M. Johnston; Peter E. Larsen - Effects of implant design and surface roughness on crestal bone and soft tissue levels in the esthetic zone The International journal of oral & maxillofacial implants. 2009;24(5):910-919.

Carlos M. Ugalde; Zhongfa Liu; Chen Ren; Kenneth K. Chan; Kapila A. Rodrigo; Yhonghua Ling; Peter E. Larsen; Guillermo E. Chacon; Gary D. Stoner; Russell J. Mumper; et al. - Distribution of anthocyanins delivered from a bioadhesive black raspberry gel following topical intraoral application in normal healthy volunteers Pharmaceutical Research. 2009;26(4):977-986.

Susan R. Mallery; Jared C. Zwick; Ping Pei; Meng Tong; Peter E. Larsen; Brian S. Shumway; Bo Lu; Henry W. Fields; Russell J. Mumper; Gary D. Stoner - Topical application of a bioadhesive black raspberry gel modulates gene expression and reduces cyclooxygenase 2 protein in human premalignant oral lesions Cancer Research. 2008;68(12):4945-4957.

Brian S. Shumway; Laura A. Kresty; Peter E. Larsen; Jared C. Zwick; Bo Lu; Henry W. Fields; Russell J. Mumper; Gary D. Stoner; Susan R. Mallery - Effects of a topically applied bioadhesive berry gel on loss of heterozygosity indices in premalignant oral lesions Clinical Cancer Research. 2008;14(8):2421-2430.

Susan R. Mallery; Gary D. Stoner; Peter E. Larsen; Henry W. Fields; Kapila A. Rodrigo; Steven J. Schwartz; Qingguo Tian; Jin Dai; Russell J. Mumper - Formulation and in-vitro and in-vivo evaluation of a mucoadhesive gel containing freeze dried black raspberries: Implications for oral cancer chemoprevention Pharmaceutical Research. 2007;24(4):728-737.