Scott R. Schricker, PhD
PhD
University of California Santa Barbara, 1997, Organic Chemistry
Development of new polymers and monomers to improve dental materials and biomaterials. Recent work has focused on improving traditional dental materials specifically glass-ionomer cements and maxillofacial prosthetics. Development of nanostructured block copolymer surfaces to control protein and cellular interactions.
My research is focused on developing novel chemistry for dental materials and biomaterials. In particular, my research has focused on incorporating nanotechnology into dental materials. Nature designs materials at the nano-level, and teeth, bone and seashells are all examples of nano-structured hard tissue. The challenge in developing synthetic nano-structured materials is not only to mimic the length scale, but to mimic the specific interactions found in nature. Enamel is over 90% mineralized and this is possible because of the highly specific interactions between the nanoscale hydroxyapatite crystals and the protein matrix. Incorporating nano fillers into dental composites results in a loading limit of around 50%. Our own work with dendrimer, hyper branched polymers and polyhedral silsesquioxanes (POSS) reveals that there is a limit as to how much nano structured material can be incorporated in a dental material. Most of my recent work has focused on harnessing the self-assembly properties of block copolymers to control the biological or host response. Block copolymers can assemble into a variety of nanoscale patterns. The goal of this work is to understand how the nano morphology of the block copolymer will affect the adhesion and conformation of proteins on its surface.
Bharat Bhushan; Scott R. Schricker - A review of block copolymer-based biomaterials that control protein and cell interactions Journal of Biomedical Materials Research - Part A. 2014;102(7):2467-2480.
Alireza Moshaverinia; Chider Chen; Kentaro Akiyama; Xingtian Xu; Winston W. L. Chee; Scott R Schricker; Songtao Shi - Encapsulated dental-derived mesenchymal stem cells in an injectable and biodegradable scaffold for applications in bone tissue engineering Journal of Biomedical Materials Research - Part A. 2013;101(11):3285-3294.
Sahar Ansari; Maryam Moshaverinia; Nima Roohpour; Winston W. L. Chee; Scott R. Schricker; Alireza Moshaverinia - Properties of a proline-containing glass ionomer dental cement Journal of Prosthetic Dentistry. 2013;110(5):408-413.
Sarah S. Mikhail; Scott R. Schricker; Shereen S. Azer; William A. Brantley; William M. Johnston - Optical characteristics of contemporary dental composite resin materials Journal of Dentistry. 2013;41(9):771-778.
Manuel L. B. Palacio; Bharat Bhushan; Scott R. Schricker - Gecko-inspired fibril nanostructures for reversible adhesion in biomedical applications Materials Letters. 2013;92:409-412.
William A. Brantley; Jie Liu; Scott R. Schricker; Fengyuan Zheng; John M. Nusstein; Masahiro Iijima; William A. T. Clark; Satish B. Alapati - Characterization of next-generation nickel-titanium rotary endodontic instruments Ceramic Transactions. 2013;242:11-18.
Alireza Moshaverinia; Chider Chen; Kentaro Akiyama; Sahar Ansari; Xingtian Xu; Winston W. Chee; Scott R. Schricker; Songtao Shi -Alginate hydrogel as a promising scaffold for dental-derived stem cells: An in vitro study Journal of Materials Science: Materials in Medicine. 2012;23(12):3041-3051.
Scott R. Schricker; Manuel L. B. Palacio; Bharat Bhushan - Review article: Designing nanostructured block copolymer surfaces to control protein adhesion Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences. 2012;370(1967):2348-2380.
M. L. B. Palacio; S. R. Schricker; B. Bhushan - Block copolymer arrangement and composition effects on protein conformation using atomic force microscope-based antigen-antibody adhesion Journal of Biomedical Materials Research - Part A. 2012;100 A(4):978-988.
Alireza Moshaverinia; B. T. S. Thirumamagal; Scott R. Schricker - Click chemistry: A potential platform for development of novel dental restorative materials Journal of Macromolecular Science, Part A: Pure and Applied Chemistry. 2012;49(4):288-292.
3001-Q Postle Hall
305 W. 12th Ave.
Columbus, OH 43210
United States