June 3, 2022

Colleagues partner for JADA Publication

Ann Griffen, DDS, MS is a professor in the Division of Pediatric Dentistry. Clifford Beall, MS, PhD is a research associate professor in the Division of Biosciences, and Eugene Leys, PhD is a professor in the Division of Biosciences. Working together -- and in collaboration with colleagues at other institutions -- they conducted research that examined Silver Diamine Fluoride (SDF), a dental material with properties that inhibit caries formation. The study explored the mechanisms by which SDF may impact the oral microbiota. Results suggested that although SDF does not significantly alter the carious surface biofilm microbial community composition, it promotes a shift in community membership deeper within dentin tubules, representing a previously unrecognized mechanism of action for SDF in caries arrest. 

Those findings were presented in volume 1 of this year's Journal of the American Dental Association's (JADA) Foundational Science publication. A premier, peer-reviewed journal that presents the best and most significant research in dentistry, JADA features research that has a significant impact on the practice of clinical dentistry. The article by Drs. Griffen, Beall, and Leys is titled Silver diamine fluoride alters microbial communities in subsurface dentin.