Research

Recent Grants and Awards

College of Dentistry researchers received over $6 million in funding for new and continuation grants and contracts in the last year (June 2016 - May 2017).

Extramural Funding

John Bartlett, MS, PhD
The role of stress and pH in fluorosis; National Institute of Dental and Craniofacial Research: $734,670

Canise Bean, DMD, MPH
Center of excellence for inter-professional education and practice (IPEP) in promoting the health and wellness of underserved populations; Ohio Department of Medicaid: $130, 807

Paul Casamassimo, DDS, MS
Lower dental midline stability: effect of primary canine loss; Delta Dental Plan of Michigan, Inc. $3,000

Hua-Hong Ben Chien, DDS, PhD
The effects of platform switching on biochemical markers of bone metabolism in peri-implant crevicular fluid; Biomet, Inc.: $3,275

Toru Deguchi, DDS, MS, PhD
Stability of self-tapping and self-drilling miniscrews by biomechanical evaluation; American Association of Orthodontists Foundation: $28,800
Comparison of the effectiveness of NiTi and TiNbTaZr archwires in initial orthodontics alignment; Delta Dental Plan of Michigan, Inc.: $2,821

Melissa Drum, DDS, MS; Sara Fowler, DDS, MS; John Nusstein, DDS, MS
Postoperative management with a steroid for symptomatic teeth diagnosed with pulpal necrosis; American Association of Endodontists Foundation: $15,000

Hany Emam, BDS, MS
The effect of parathyroid hormone analogues when added to mineralized bone xenografts; American Academy of Implant Dentistry Research Foundation: $20,000

Allen Firestone, DDS, MS
Dental arch width and length parameters in patients with obstructive sleep apnea versus patients without; Delta Dental Plan of Michigan, Inc.: $15,907
Investigation into daily Invisalign tray wear duration; Align Technology, Inc.: $31,815

Brian Foster, PhD
Extracellular matrix and phosphate/pyrophosphate metabolism in cementum formation; National Institute of Arthritis and Musculoskeletal and Skin Diseases: $249,000
Dentalalveloar disease associated with HPP; Soft Bones, Inc. $25,000

Ann L. Griffen, DDS, MS
Acquisition of the Human Oral Microbiome; National Institute of Dental and Craniofacial Research: $385,000

Rachel Kearney, BSDH, MS
Effectiveness of a natural, non-peroxide tooth whitening gel; SafeWhite, Inc. $19,018

Do-Gyoon Kim, MS, PhD
Dynamic mechanical stability of Trabecular Metal ™ dental implants; Zimmer, Inc. $10,287
Nanoindentation-based characterization of peri-implant bone quality in canine fresh extraction sockets; Zimmer, Inc. $35,312
Dynamic mechanical stability of Trabecular Metal ™ dental implants; Zimmer, Inc. $10,287

Lisa Knobloch, DDS, MS
A prospective study to evaluate Astra Tech Osseospeed 3.0S implants and Atlantis abutments for restoration of a lateral incisor in cleft patients; Astra Tech: $15,000

Purnima Kumar, BDS, MS, PhD
A randomized cross-over design study to assess the effect of two home oral hygiene regimens on peri-implant muscositis; Philips Oral Healthcare, Inc.: $342,206
Interactive omics: black raspberry metabolites and the oral microbiome in smokers; National Cancer Institute: $366,984

Peter Larsen, DDS
Pathway CH2: sphenopalative ganglion stimulation for the treatment of chronic cluster headaches; Autonomic Technologies, Inc. $77,029

Binnaz Leblebicioglu, DDS, MS, PhD
Identification of host-related risk factors for peri-implant tissue loss; Osseointegration Foundation: $30,000
In vitro engineered soft tissue model to study peri-implant pathogenesis; Zimmer Biomet: $26,000

Eugene J. Leys, PhD
Polymicrobial oral bacteria host interactions in a high throughput model; National Institute of Dental and Craniofacial Research: $385,000
The oral microbiome in HIV-associated oral warts and candidiasis; subcontract with Louisiana State University (National Institute of Dental and Craniofacial Research): $221,242
Culturing of the uncultured: reverse genomics and multispecies consortia in oral health and disease; subcontract with University of Tennessee-Batelle, LLC (National Institute of Dental Craniofacial Research): $172,686

Susan Mallery, DDS, MS, PhD
Evaluation of locally-delivered fenretinide and black raspberries for oral cancer; National Institute of Dental and Craniofacial Research: $318,056
Secondary Chemoprevention of Oral Cancer by Locally Delivered Agents; National Cancer Institute; $366,984
Effects of sustained smokeless tobacco use on salivary gland tissues; Casey-Gerry: $12,630

John Nusstein, DDS, MS; Melissa Drum, DDS, MS
An evaluation of 4% prilocaine plus 2% lidocaine with 1:100,000 epinephrine for inferior alveolar nerve blocks; American Association of Endodontists Foundation: $9,357

Sara Palmer, PhD
Genetics and Genomics of the yidC paralogs in Streptococcus Mutans; National Institute of Dental and Craniofacial Research: $249,000
Probiotics that moderate pH and antagonize pathogens to promote oral health; subcontract with University of Florida (National Institute of Dental and Craniofacial Research): $9,245

Ning Quan, MS, PhD
Anxiety, IL-1R1 and neuroinflammation; National Institute of Mental Health: $250,000
The role of intestinal microbiome in anxiety and depression; subcontract with McMaster University (National Institute of Mental Health): $12,114

Scott Schricker, PhD
Development of non-foaming and high strength, single component methacrylate/polyurethane adhesive; Elmer’s Products, Inc.: $106,761

John Sheridan, MS, PhD
Brain region dependent trafficking of myeloid precursor cells in repeated defeat; National Institute of Mental Health: $499,135
Comprehensive training in oral and craniofacial sciences; National Institute of Dental and Craniofacial Research: $481,950
Role of stress-induced reduction in Lactobacillus Reuteri on colonic inflammation; subcontract with Nationwide Children’s Hospital (National Center for Complementary and Integrative Health): $53,804
Social regulation of pro-inflammatory monocytes; subcontract with University of California (National Institute on Aging): $70,070

Susan Travers, MS, PhD; Joseph Travers, MS, PhD
Inhibitory modulation and circuitry in the rostral solitary nucleus; National Institute of Dental and Craniofacial Research: $328,844
Psychophysical evaluation of taste function; subcontract with Florida State University (National Institute on Deafness and Other Communication Disorders): $153,464

Burak Yilmaz, DDS, PhD
Displacement comparison of two different abutments to implants with conical internal connections; DENTSPLY International: $2,000
Locator ™ legacy versus Locator R-Tx ™: evaluation of performance and biofilm; Zest Anchors: $3,000

Fengyuan Zheng, BDS, PhD
The effect of angular misfit on implant positional stability upon splinted multiunit implant supported fixed prosthesis; American College of Prosthodontists: $25,000

Intramural Funding: Seed and Pilot Grants

Rabia Arif, DDS, MS
Color stability of new CAD/CAM materials after staining and accelerated aging: $1,275

Binnaz Leblebicioglu, DDS, PhD
Identification of host related risk factors for peri-implant tissue loss: $15,000

Damian Lee, DDS, MS
Differences of oral bone quality in partially edentulous arch: $24,750

Maiko Suzuki, DDS, PhD
Epigentic and non-Epigenetic role of SIRT - 1 in fluoride-induced cell stress: $30,000

Burak Yilmaz, DDS, PhD
Validity of different digital camera systems for color communication: $7,785