Research

Recent Grants and Awards

College of Dentistry researchers received over $4.5 million in funding for new and continuation grants and contracts in the last year (July 1, 2017 - June 30, 2018).

Extramural Funding​

Hua-Hong Ben Chien, DDS, PhD
The effects of platform switching on biochemical markers of bone metabolism in peri-implant crevicular fluid; Zimmer Biomet: $5,895

Bryant Cornelius, DDS, MBA, MPH
Stability of epinephrine in a 0.9% saline solution; American Society of Dentist Anesthesiologists: $3,700

Henry Fields, DDS, MS, MSD
Orthodontic informed consent considering effect of rehearsal of treatment risk on short- and long-term recall and comprehension; Delta Dental Foundation of Michigan, Inc.: $3,000

Allen Firestone, DDS, MS
Investigation into daily Invisalign® tray wear duration; Align Technology, Inc.: $31,815

Multifactorial approach to increasing oral appliance adherence in OSA (obstructive sleep apnea) treatment; American Sleep Medicine Foundation: $28,339

Pain after initial archwire placement: A randomized clinical trial comparing conventional and alternative treatments; Delta Dental Foundation of Michigan, Inc.: $3,000

Brian Foster, MS, PhD
Extracellular matrix and phosphate/pyrophosphate metabolism in cementum formation; National Institute of Arthritis and Musculoskeletal and Skin Diseases: $249,000

Ann L. Griffen, DDS, MS
Acquisition of the Human Oral Microbiome; National Institute of Dental and Craniofacial Research: $385,000

Microbial pioneers – acquisition and establishment of the subgingival microbiome; American Academy of Pediatric Dentistry: $4,000

Kimberly Hammersmith, DDS, MPH, MS
The effectiveness of silver diamine fluoride treatment on interproximal dental caries arrest; Delta Dental
Foundation of Michigan, Inc.: $3,000

Rachel Kearney, BSDH, MS
A qualitative study: An evaluation of the perception of Ohio dental hygienists that work in nursing home facilities with the elderly population and use the oral health access supervision act permit; International Federation of Dental Hygienists: $1,029

Do-Gyoon Kim, MS, PhD
Nanoindentation-based characterization of peri-implant bone quality in canine fresh extraction sockets; Zimmer, Inc.: $18,614

Characteristics of peri-implant bone quality with guided bone regeneration; Delta Dental Foundation of Michigan: $3,000

Ashok Kumar, BDS, MS
Comparing post-op comfort following dental rehab under general anesthesia; Delta Dental Foundation of Michigan, Inc.: $2,000

Purnima Kumar, BDS, MS, PhD
A randomized cross-over design study to assess the effect of two home oral hygiene regimens on peri-implant muscositis; Philips Oral Healthcare, Inc.: $136,043

Interactive omics: black raspberry metabolites and the oral microbiome in smokers; National Cancer Institute: $312,077

E-cigarettes and perturbations in the subgingival ​ecosystem; National Institute of Dental and Craniofacial Research: $624,724

Peter Larsen, DDS
Pathway CH2: sphenopalative ganglion stimulation for the treatment of chronic cluster headaches; Autonomic Technologies, Inc.: $22,526

Binnaz Leblebicioglu, DDS, MS, PhD
In vitro engineered soft tissue model to study peri-implant pathogenesis; Zimmer Biomet: $10,000

Eugene J. Leys, MS, PhD
Polymicrobial oral bacteria host interactions in a high throughput model; National Institute of Dental and Craniofacial Research: $770,000

The oral microbiome in HIV-associated oral warts and candidiasis; subcontract with Louisiana State University (National Institute of Dental and Craniofacial Research): $195,589

Culturing of the uncultured: reverse genomics and multispecies consortia in oral health and disease; subcontract with University of Tennessee-Batelle, LLC (National Institute of Dental Craniofacial Research): $327,198

Susan Mallery, DDS, MS, PhD
Secondary Chemoprevention of Oral Cancer by Locally Delivered Agents; National Cancer Institute: $650,788

Field-coverage oral cancer chemoprevention via Janus nanoparticles; Fanconi Anemia Research Fund, Inc.: $12,568

Assessment of Fenretinide+Tocilizumab Nanoparticles’ Chemopreventive Efficacy in an Oral Carcinogenesis Murine Model; OSUCCC Pelotonia grant: $150,000

Ning Quan, MS, PhD
The role of intestinal microbiome in anxiety and depression; subcontract with McMaster University (National Institute of Mental Health): $11,989

John Sheridan, MS, PhD
Brain region dependent trafficking of myeloid precursor cells in repeated defeat; National Institute of Mental Health: $31,469

Comprehensive training in oral and craniofacial sciences; National Institute of Dental and Craniofacial Research: $415,290

Social regulation of pro-inflammatory monocytes; subcontract with University of California (National Institute on Aging): $70,070

Zongyang Sun, DDS, MS, MSD, PhD
Assessing TAD-tooth root proximity with CBCT imaging: Is it accurate and is metal artifact reduction algorithm effective; Delta Dental
Foundation of Michigan: $3,000

Maiko Suzuki, DDS, PhD
Epigenetic and non-epigenetic role of SIRT1 in fluoride-induced cell stress; National Institute of Dental & Craniofacial Research: $379,060

Joseph Travers, MS, PhD and Susan Travers, MS, PhD
Inhibitory modulation and circuitry in the rostral​ solitary nucleus; National Institute on Deafness & Other Communication Disorders: $327,969

Burak Yilmaz, DDS, PhD
The accuracy of different digital impression techniques and scan bodies for complete arch, implant-supported reconstructions; American Academy of Fixed Prosthodontics: $4,000

Intramural Funding: Seed and Pilot Grants

Brian Foster, MS, PhD
Functions of discoidin domain receptor 1 (DDR1) in periodontal health and disease: $21,291

Zongyang Sun, DDS, MS, MSD, PhD
Improve bone marrow aspirate concentrate with a local self-healing injury: $25,000

Burak Yilmaz, DDS, PhD
Fracture analysis of high density and high performance polymers used for implant-supported fixed, cantilevered prostheses: $10,595